Castelleone is a comune (municipality) in the Province of Cremona in the Italian region Lombardy, located about 50 km southeast of Milan and about 30 km northwest of Cremona. As of 31 December 2004, it had a population of 9,088 and an area of 45.0 km². Castelleone borders the following municipalities: Cappella Cantone, Fiesco, Gombito, Izano, Madignano, Ripalta Arpina, San Bassano, Soresina, Trigolo.