Orizaba is a city and municipality in the Mexican state of Veracruz. It is located 20 km west of its sister city Córdoba, and is adjacent to Río Blanco and Ixtaczoquitlán, on Federal Highways 180 and 190. The name Orizaba comes from a Hispanized pronunciation of the Nahuatl (Aztecan) name Ahuilizapan [āwil-lis-ā-pan], which means (more or less) "place of playing waters". The town lies at 1200 m. (4000 ft.), at the confluence of the Río Blanco with several tributaries, including the Río Orizaba, near the mouth of a large valley heading westward into the eastern Sierra Madre. This location, at the bottom of the ascent into the mountains, is an important transition point along what has been for centuries the main trade route between Mexico City and Veracruz on the Gulf Coast. The climate is generally pleasant, though often cloudy and rainy, and the soil of the Orizaba valley is extraordinarily fertile. Overlooking the valley from the north is the Pico de Orizaba (Citlaltépetl), a volcano that, at 5636 m. (18,490 ft.), is the highest mountain in Mexico and third highest in North America. In the town of Ixhuatlancillo north of Orizaba, and in a large mountainous area to the south (the Sierra de Zongolica), live many thousands of people who speak a variant of Nahuatl which is often called Orizaba Nahuatl [ ISO code nlv]. Orizaba was already an important town at the time of the Spanish conquest, and it was in Orizaba that La Malinche, Hernán Cortés's interpreter and mistress, was married to the Spanish gentleman Juan Jaramillo. A plaque in Orizaba commemorates this event.